Hydroxychloroquine

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1 Hydroxychloroquine Effectiveness Against COVID-19

Treatments and Protocols


"both CQ and HCQ could inhibit the transport of SARS-CoV-2 along the endocytic pathway via neutralizing the pH value of acidic organelles (endosome and lysosome) in host cells, which have been verified by several in vitro studies."

Source: Hydroxychloroquine/Chloroquine as Therapeutics for COVID-19: Truth under the Mystery, April 2021

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8071775/

https://archive.md/vXqbh


"HCQ is consistently effective against COVID-19 when provided early in the outpatient setting, it is overall effective against COVID-19, it has not produced worsening of disease and it is safe."

Source: Hydroxychloroquine is effective, and consistently so when provided early, for COVID-19: a systematic review, November 2020

https://pubmed.ncbi.nlm.nih.gov/33042552/

https://archive.md/0m0aa


"These data demonstrate that addition of HCQ on top of the basic treatments is highly effective in reducing the fatality of critically ill patients of COVID-19 through attenuation of inflammatory cytokine storm."

Source: Low Dose of Hydroxychloroquine Reduces Fatality of Critically Ill Patients With COVID-19, May 2020

https://pubmed.ncbi.nlm.nih.gov/32418114/

https://archive.md/bleOa


"the third category confines to the inflammation in the form of cytokine storm and severe ARDS take over; therefore, using CQ/HCQ treatment at this stage would be beneficial owing to the reports it can overcome cytokine storm and improves ARDS."

Source: Exploring insights of hydroxychloroquine, a controversial drug in Covid-19: An update, May 2021

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959684/

https://archive.md/z74d3


"Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds."

Source: Chloroquine Is a Potent Inhibitor of SARS Coronavirus Infection and Spread, August 2005

https://pubmed.ncbi.nlm.nih.gov/16115318/

https://archive.ph/YobdJ

2 HCQ Success Stories

"Hydroxychloroquine: the drug Costa Rica uses successfully to fight covid-19"

https://c-vine.com/blog/hydroxychloroquine-the-drug-costa-rica-uses-successfully-to-fight-covid-19/

https://archive.ph/Fp1Ba


"Novartis will donate hydroxychloroquine for 20 thousand patients in Mexico"

https://www.elsoldemexico.com.mx/doble-via/salud/novartis-donara-hidroxicloroquina-para-20-mil-pacientes-en-mexico-5258767.html

https://archive.ph/ZWLhA


"Apotex, Canada’s largest pharmaceutical company, announced today that it is donating Hydroxychloroquine to accelerate a study examining if it prevents infection of COVID-19 in front-line healthcare employees."

https://www1.apotex.com/global/about-us/press-center/2020/03/23/apotex-donates-hydroxychloroquine-for-a-clinical-study-to-prevent-infection-from-covid-19-with-front-line-health-care-workers

https://archive.ph/Vz3TH

June 8, 2021: "Hydroxychloroquine really works says Professor of Medicine Dr Peter McCullough, describing the treatment as “the most widely used therapeutic” to treat COVID-19 in the world. “The chances that it doesn’t work are calculated to be one in 17 billion,” he told Sky News. “There’s no controversy over whether or not hydroxychloroquine works. The controversy is on the public health approach to COVID-19.""

‘Only a one in 17 billion chance hydroxychloroquine doesn’t work’: medical professor

https://www.skynews.com.au/details/_6212859932001

https://web.archive.org/web/20210608114749/https://www.skynews.com.au/details/_6212859932001

2.1 HCQ Suppression

Hit studies on HCQ retracted:

"Two elite medical journals retract coronavirus papers over data integrity questions"

https://www.science.org/news/2020/06/two-elite-medical-journals-retract-coronavirus-papers-over-data-integrity-questions

https://archive.ph/WXyNk

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2 Additional Resources

3 Recent Changes


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