Treatments and Protocols
1 Treatments
Get a prescription for ivermectin or hydroxychloroquine from America's Frontline Doctors:
https://speakwithanmd.com/americasfrontlinedoctors/
“Under an EUA, FDA may allow the use of unapproved medical products, or unapproved uses of approved medical products in an emergency to diagnose, treat, or prevent serious or life-threatening diseases or conditions when certain statutory criteria have been met, including that there are no adequate, approved, and available alternatives”
https://www.fda.gov/vaccines-blood-biologics/vaccines/emergency-use-authorization-vaccines-explained
"The Right to Try Act, or the Trickett Wendler, Frank Mongiello, Jordan McLinn, and Matthew Bellina Right to Try Act, was signed into law May 30, 2018. This law is another way for patients who have been diagnosed with life-threatening diseases or conditions who have tried all approved treatment options and who are unable to participate in a clinical trial to access certain unapproved treatments."
https://www.fda.gov/patients/learn-about-expanded-access-and-other-treatment-options/right-try
https://www.fda.gov/media/133864/download
https://web.archive.org/web/20200617102841/https://www.fda.gov/media/133864/download
1.1 Ivermectin
Visit Ivermectin for efficacy students. Protocols are outlined below.
1.2 Hydroxychloroquine
Visit Hydroxychloroquine for efficacy students. Protocols are outlined below.
1.3 Chlorine Dioxide Solution
Visit Chlorine Dioxide Solution for efficacy students. Protocols are outlined below.
1.4 Vitamin C
"Overall, vitamin C exhibits plausible mechanisms of action that are of relevance to severe respira tory infection, including antioxidant, anti-inflammatory, antithrombotic, and immuno-modulatory functions. Based on the findings from clinical trials of patients with pneumonia and sepsis, and preliminary observational and interventional studies of COVID-19 patients, it is likely that vitamin C administration will improve outcomes in COVID-19."
2020-11: The Emerging Role of Vitamin C in the Prevention and Treatment of COVID-19, Nutrients. 2020 Nov; 12(11): 3286.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693980/
"Up to 82% critically ill patients had low Vitamin C values"
2021-07-09: Pujol University Hospital, Badalona, Spain
https://pubmed.ncbi.nlm.nih.gov/34243781/
"Restoring and maintaining healthy levels of ascorbic acid [vitamin C], selenocysteine, vitamin D, and NAD is critical in the battle against SARS-CoV-2."
2021-07-18: Vitamin C Levels in Critically Ill Covid-19 Patients
http://orthomolecular.org/resources/omns/v17n17.shtml
"Vitamin C should not be seen as a sole cure for SARS-CoV-2 but it does provide the immune system the necessary boost to combat it more efficiently, shorten the length of the disease and prevent fatal complications."
2021-10-01: International Society for Orthomolecular Medicine, Volume 36, Number 3, 2021
1.5 Vitamin D
"New Study Found 80% of COVID-19 Patients Were Vitamin D Deficient"
2020-09-03: Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2770157
"The two datasets provide strong evidence that low D3 is a predictor rather than a side effect of the infection. Despite ongoing vaccinations, we recommend raising serum 25(OH)D levels to above 50 ng/ml to prevent or mitigate new outbreaks due to escape mutations or decreasing antibody activity."
2021-09-22: COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis, September 2021
https://www.medrxiv.org/content/10.1101/2021.09.22.21263977v1
1.6 N-acetyl-L-cysteine
Current NAC Clinical Trials: https://www.clinicaltrials.gov/ct2/results?cond=COVID&term=N-acetyl+cysteine&cntry=&state=&city=&dist=
"N-acetylcysteine (NAC) is inexpensive, has very low toxicity, has been FDA approved for many years, and has the potential to improve therapeutic strategies for COVID-19. NAC administered intravenously, orally, or inhaled, may suppress SARS-CoV-2 replication and may improve outcomes if used timely."
2020-11-05: N-Acetylcysteine to Combat COVID-19: An Evidence Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649937/
"N-acetylcysteine did not prevent A/H1N1 virus influenza infection but significantly reduced the incidence of clinically apparent disease."
1997-07-01: Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment
https://erj.ersjournals.com/content/10/7/1535
"experiments using pulmonary arterial ECs infected with Pseu-Spike which was rescued by treatment with N-acetyl-L-cysteine"
2021-03-21: SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2, March 2021
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902
“NAC has anticoagulant and platelet-inhibiting properties.”
2006-01-17: The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm
https://pubmed.ncbi.nlm.nih.gov/16607076/
"We hypothesize that NAC could act as a potential therapeutic agent in the treatment of COVID-19 through a variety of potential mechanisms, including increasing glutathione, improving T cell response, and modulating inflammation. In this article, we present evidence to support the use of NAC as a potential therapeutic agent in the treatment of COVID-19."
2020-10: N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2
https://www.sciencedirect.com/science/article/abs/pii/S0306987720308811
“FDA has concluded that NAC products are excluded from the dietary supplement definition under section 201(ff)(3)(B)(i) of the Act [21 U.S.C. § 321(ff)(3)(B)(i)]. Under this provision, if an article (such as NAC) has been approved as a new drug under section 505 of the Act [21 U.S.C. § 355], then products containing that article are outside the definition of a dietary supplement, unless before such approval that article was marketed as a dietary supplement or as a food. NAC was approved as a new drug under section 505 of the Act [21 U.S.C. § 355] on September 14, 1963. FDA is not aware of any evidence that NAC was marketed as a dietary supplement or as a food prior to that date.”
2020-07-23: WARNING LETTER, Vita Heaven, LLC dba Hangover Heaven, MARCS-CMS 593765
Other NAC benefits
2018-02-16: N-Acetyl Cysteine: a Biohack for those who have succumbed to Vice
https://roselandj.medium.com/n-acetyl-cysteine-1ca09f0d6a1f
1.7 Cannabidiol
"Our results suggest that CBD can block SARS-CoV-2 infection at early stages of infection, and CBD administration is associated with a lower risk of SARS-CoV-2 infection in humans."
2021-03-10: Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7987002/
1.8 Nicotine
"Nicotine up-regulates the ACE/angiotensin (ANG)-II/ANG II type 1 receptor axis, and down-regulates the compensatory ACE2/ANG-(1–7)/Mas receptor axis"
"we suggest that smoking may promote cellular uptake mechanisms of SARS CoV-2 through α7-nAChR signaling"
Source: COVID-19 and Smoking. Is Nicotine the Hidden Link?, European Respiratory Journal, 2020
https://erj.ersjournals.com/content/55/6/2001116
Nicotine may bind with the ACE2 receptor, particularly in people with COVID-19, and thus could interfere with further SARS-CoV-2-ACE2 binding
Source: A computational insight of the improved nicotine binding with ACE2-SARS-CoV-2 complex with its clinical impact, April 2020
https://arxiv.org/abs/2004.14943
"Daily active smokers are rare among outpatients or hospitalized COVID-19 patients. . . . Several arguments suggest that nicotine could be responsible for this protective effect thank to the nicotinic acetylcholine receptor (nAChR)."
Source: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients (NICOVID), December 2020
https://clinicaltrials.gov/ct2/show/NCT04608201
"Nicotine may inhibit the penetration and spread of the virus and have a prophylactic effect in COVID-19 infection."
Source: Efficacy of Nicotine in Preventing COVID-19 Infection (NICOVID-PREV), February 2021
https://clinicaltrials.gov/ct2/show/NCT04583410
1.9 Fluvoxamine
Fluvoxamine helps in COVID treatment: "In this randomized trial that included 152 adult outpatients with confirmed COVID-19 and symptom onset within 7 days, clinical deterioration occurred in 0 patients treated with fluvoxamine vs 6 (8.3%) patients treated with placebo over 15 days, a difference that was statistically significant."
Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19, December 8, 2020
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662481/
Fluvoxamine has anti-inflammatory properties that can help treat COVID: "This review illustrates mechanisms of action underlying anti-inflammatory and antiviral properties of FLV."
Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19, April 20, 2021
https://www.frontiersin.org/articles/10.3389/fphar.2021.652688/full
Fluvoxamine targets sigma-1 to stop SARS-CoV-2 replication: "Knockout and knockdown of SIGMAR1 (sigma-1 receptor, encoded by SIGMAR1) caused robust reductions in SARS-CoV-2 replication, which indicates that the sigma-1 receptor is a key therapeutic target for SARS-CoV-2 replication. Interestingly, a recent clinical trial demonstrated that treatment with the antidepressant fluvoxamine, which has a high affinity at the sigma-1 receptor, could prevent clinical deterioration in adult outpatients infected with SARS-CoV-2. In this review, we discuss the brief history of the sigma-1 receptor and its role in SARS-CoV-2 replication in cells."
Repurposing of CNS drugs to treat COVID-19 infection: targeting the sigma-1 receptor, January 5, 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785036/
1.10 Other Treatments
Regulatory bodies approve dexamethasone as covid treatment
Antihistamines, including the Benadryl brand, found effective against SARS-CoV-2
"Three of the drugs — hydroxyzine, diphenhydramine and azelastine — showed direct, statistically significant antiviral effects on the SARS-CoV-2 virus."
"Among the three medications, azelastine was found to inhibit the SARS-CoV-2 virus at a dose that was smaller than the amount prescribed as a nasal spray. The other two antihistamines required higher drug concentrations than currently recommended dosing levels to achieve antiviral activity in cells."
Source: Existing antihistamine drugs show effectiveness against COVID-19 virus in cell testing, University of Florida Health Department
"Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests"
Source: Oxford University
2 Protocols
Ivermectin and Hydroxychloroquine are covered in the FLCCC protocols, and Andreas Kalcker has the latest research for Chlorine Dioxide.
World Council for Health Early COVID-19 Treatment Guidelines: A Practical Approach to Home-based Care for Healthy Families
2.1 Front Line COVID-19 Critical Care Alliance Treatment Protocols
FLCCC Alliance I-MASK+ Protocol for Prevention & Early Outpatient Treatment Protocol for COVID-19
https://covid19criticalcare.com/covid-19-protocols/i-mask-plus-protocol/
FLCCC Alliance I-MASS Protocol for Prevention & At Home Treatment Mass Distribution for COVID-19
FLCCC Alliance MATH+ Protocol for Hospital Treatment for COVID-19, for use by professionals
https://covid19criticalcare.com/covid-19-protocols/math-plus-protocol/
FLCCC Alliance iRecover Protocol for treatment of Long Haul Covid-19
https://covid19criticalcare.com/covid-19-protocols/i-recover-protocol/
FLCCC Alliance list of Ivermectin-friendly COVID-19 Care Providers
https://covid19criticalcare.com/ivermectin-in-covid-19/covid-19-care-providers/
2.2 Andreas Kalcker CDS Protocols
https://andreaskalcker.com/en/cds-clo2/cds-protocols.html
https://web.archive.org/web/20210605051010/https://andreaskalcker.com/en/cds-clo2/cds-protocols.html
https://andreaskalcker.com/en/coronavirus/protocols.html
2.3 Zelenko Protocol
https://vladimirzelenkomd.com/wp-content/uploads/2021/08/Treatment_Protocol.pdf
2 Additional Resources
- Table of Contents
- Download Archived Sources
- Follow VerifyWiki on Gab: https://gab.com/VerifyWiki
3 Recent Changes
