Vaccine Ineffectiveness
1 Vaccine Ineffectiveness
Recent research from the Cleveland Clinic shows your risk of contracting COVID-19 goes up with the number of vaccines you receive.
"The risk of COVID-19 also increased with time since the most recent prior COVID-19 episode and with the number of vaccine doses previously received."
Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine
https://academic.oup.com/ofid/article/10/6/ofad209/7131292?login=false
"BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines."
https://www.cdc.gov/respiratory-viruses/whats-new/covid-19-variant.html
Vaccinated make up vast majority of covid hospitalizations
https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-09-12/03-COVID-Havers-508.pdf
Vaccinated Remain Vulnerable:
2021 July 8: "Covid cases in England are THIRTEEN times higher in young people compared to over-60s in more proof of 'vaccine effect' and infections rose in every town except three last week, official figures show"
Vaccinated can still get and spread the virus or variants: "The SARS-CoV-2 Delta variant and its sublineages can cause high viral loads, are highly transmissible, and contain mutations that confer partial immune escape"
"68% of individuals infected despite vaccination tested positive with Ct <25, including at least 8 who were asymptomatic at the time of testing. Our data substantiate the idea that vaccinated individuals who become infected with the Delta variant may have the potential to transmit SARS-CoV-2 to others."
Source: Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent - Wisconsin, July 2021
https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v3
"A full course of the Pfizer-BioNTech vaccine was just 39% effective at preventing infections and 41% effective at preventing symptomatic infections caused by the Delta Covid-19 variant" down from 95% effectiveness in July.
July 23 article: https://archive.ph/AESrV
July 6 article: https://archive.ph/774qN
Israel source: https://www.ynet.co.il/news/article/rJQ1O5kp00#autoplay
"Only modest differences in vaccine effectiveness were noted with the delta variant as compared with the alpha variant after the receipt of two vaccine doses. This finding would support efforts to maximize vaccine uptake with two doses among vulnerable populations."
Source: The New England Journal of Medicine, Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant, July 2021
https://www.nejm.org/doi/full/10.1056/NEJMoa2108891#.YPizFxz-Nbs.twitter
"At the country-level, there appears to be no discernable relationship between percentage of population fully vaccinated and new COVID-19 cases in the last 7 days. In fact, the trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people. Notably, Israel with over 60% of their population fully vaccinated had the highest COVID-19 cases per 1 million people in the last 7 days."
"[Iceland and Portugal] have over 75% of their population fully vaccinated and have more COVID-19 cases per 1 million people than countries such as Vietnam and South Africa that have around 10% of their population fully vaccinated."
Source: Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States, European Journal of Epidemiology, 2021
https://link.springer.com/article/10.1007/s10654-021-00808-7
"people who were vaccinated in January and February were, in June, July, and the first half of August, six to 13 times more likely to get infected than unvaccinated people who were previously infected with the coronavirus. In one analysis, comparing more than 32,000 people in the health system, the risk of developing symptomatic COVID-19 was 27 times higher among the vaccinated, and the risk of hospitalization eight times higher."
Source: Having SARS-CoV-2 once confers much greater immunity than a vaccine—but vaccination remains vital, August 2021
"SARS-CoV-2-naïve vaccinees had a 13.06-fold (95% CI, 8.08 to 21.11) increased risk for breakthrough infection with the Delta variant compared to those previously infected"
"This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity."
Source: Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1
Efficacy drops 2 months after getting Covaxin, 3 months after Covishield
Source: Persistence of antibodies against Spike glycoprotein of SARS-CoV-2 in health care workers post double dose of BBV-152 and AZD1222 vaccines,
https://www.researchsquare.com/article/rs-888762/v1
"Antispike, anti-RBD and neutralization levels dropped more than 84% over 6 months’ time in all groups irrespective of prior SARS-CoV-2 infection."
Source: Significant reduction in humoral immunity among healthcare workers and nursing home residents 6 months after COVID-19 BNT162b2 mRNA vaccination
https://www.medrxiv.org/content/10.1101/2021.08.15.21262067v3.full.pdf
95% vaccinated Harvard Business School experiences COVID surge
"Harvard Business School Moves MBA Classes Online As Covid Cases Surge"
Covid-19 in Wales: A third of positive cases are unvaccinated
https://www.bbc.com/news/uk-wales-58680204
"Breakthrough hospitalizations a reflection of Maine’s high vaccination rate"
"Israel is being closely watched now because it was one of the first countries out of the gate with vaccinations in December 2020 and quickly achieved a degree of population coverage that was the envy of other nations— for a time."
Source: A grim warning from Israel: Vaccination blunts, but does not defeat Delta
https://www.sciencemag.org/news/2021/08/grim-warning-israel-vaccination-blunts-does-not-defeat-delta
"Despite 95% vaccination rate, Cornell today has five times more COVID cases than it did this time last year"
"Nearly 60% of hospitalized COVID-19 patients in Israel fully vaccinated, data shows"
October 26, 2020: Fauci: Early COVID-19 vaccines will only prevent symptoms, not block the virus
July 7, 2021: Top health expert says vaccinated people are spreading delta variant
July 26, 2021: Higher COVID Rate Found In Counties With Higher Vaccination Rate
July 20, 2021: "Sixth Texas Dem tests positive for COVID after fleeing state to block GOP voting bill"
Double vaccinated hospital workers getting COVID
Iceland's COVID data shows majority of COVID cases are fully-vaccinated
https://web.archive.org/web/20220125051310/https://www.covid.is/data
July 19, 2021: 60% of people being admitted to UK hospitals are unvaccinated - adviser
August 6, 2021: CDC admits that 74% of positive cases in Barnstable County Massachusetts were fully vaxxed
Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021
https://www.cdc.gov/mmwr/volumes/70/wr/mm7031e2.htm
July 21, 2021: Vaccine failures resulting in hundreds of hospitalizations in Illinois
159 Dead, 593 Hospitalized in Illinois Breakthrough COVID Cases
May 25, 2021: CDC started pursuing asymmetric reporting of COVID cases in May 2021 will not investigate mild cases of covid in vaccinated individuals, allowing narrative that this is a pandemic of the unvaccinated
C.D.C. Will Not Investigate Mild Infections in Vaccinated Americans
July 27, 2017: CDC warns COVID-19 may be a few mutations away from evading vaccines
https://nypost.com/2021/07/27/cdc-covid-19-may-be-a-few-mutations-away-from-evading-vaccines/
Antibodies from vaccines start to drop within 6 months
"In individuals who had not previously been infected with SARS-CoV-2, a single dose of either the Pfizer or the AstraZeneca vaccine induced a barely detectable level of neutralizing antibodies against the Delta variant. About 10% of the sera neutralized this variant."
"Our results demonstrate that the emerging Delta variant partially—but notably—escapes neutralizing monoclonal antibodies and polyclonal antibodies elicited by previous infection with SARS-CoV-2 or by vaccination."
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization, July 8, 2021
https://www.nature.com/articles/s41586-021-03777-9
Vaccine effectiveness against SARS-CoV-2 infection with the Omicron or Delta variants following a two-dose or booster BNT162b2 or mRNA-1273 vaccination series: Danish cohort study
https://www.medrxiv.org/content/10.1101/2021.12.20.21267966v1
https://www.medrxiv.org/content/10.1101/2021.12.20.21267966v1.full.pdf
"As this field continues to develop, clinicians and public health practitioners should consider vaccinated persons who become infected with SARS-CoV-2 to be no less infectious than unvaccinated…”
Transmission potential of vaccinated and unvaccinated persons infected with the SARS-CoV-2 Delta
https://www.medrxiv.org/content/10.1101/2021.11.12.21265796v1.full
https://www.medrxiv.org/content/10.1101/2021.11.12.21265796v1.full.pdf
Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity source
"[N]o statistically significant difference in infection rates between the masked and unmasked group in any of the trials."
Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity
https://jamanetwork.com/journals/jama/fullarticle/2786039
"In this study, 11 participants exhibit S1 antigen in plasma after the first injection, whereas nucleocapsid concentrations are insignificant in all participants, confirming that the detected S1 originates from vaccination and not natural infection. The presence of S1 is likely due to the nature of the encoded mRNA-1273 spike protein, which contains a cleavable S1–S2 site and enables release of S1 from the spike trimer [2]. We hypothesize that release of S1 protein could result from cleavage via mammalian cell proteases or circulating proteases. "
Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients
https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab465/6279075
Statistician on the latest UK data: "The vaccines have NO REAL efficacy. Even worse, they have come at the expense of hundreds of thousands of serious adverse events in the UK alone (possibly over a million). It appears that these vaccines are killing more people than they save."
https://roundingtheearth.substack.com/p/uk-data-shows-no-all-cause-mortality
California ‘Epsilon’ strain of COVID-19 could evade vaccines, study says, July 7, 2021
https://nypost.com/2021/07/07/california-epsilon-strain-of-covid-19-could-evade-vaccines-study/
https://www.science.org/doi/10.1126/science.abi7994
Fears arise that lambda COVID-19 variant from Peru may be resistant to vaccines, June 5, 2021
https://nypost.com/2021/07/05/fears-arise-that-lambda-covid-variant-may-be-resistant-to-vaccines/
Outbreak reported at Rhode Island hospital after Covid-positive, asymptomatic staff asked to work
https://bhddh.ri.gov/eleanor-slater-hospital/contact-hospital
‘Striking’ vaccine resistance in Omicron variant: Columbia University
https://nypost.com/2021/12/16/columbia-university-finds-omicron-vaccine-resistance/
Study: Striking Antibody Evasion Manifested by the Omicron Variant of SARS-CoV-2
https://www.biorxiv.org/content/10.1101/2021.12.14.472719v1
https://www.biorxiv.org/content/10.1101/2021.12.14.472719v1.full.pdf
"At the country-level, there appears to be no discernable relationship between percentage of population fully vaccinated and new COVID-19 cases in the last 7 days (Fig. 1). In fact, the trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people. Notably, Israel with over 60% of their population fully vaccinated had the highest COVID-19 cases per 1 million people in the last 7 days. The lack of a meaningful association between percentage population fully vaccinated and new COVID-19 cases is further exemplified, for instance, by comparison of Iceland and Portugal. Both countries have over 75% of their population fully vaccinated and have more COVID-19 cases per 1 million people than countries such as Vietnam and South Africa that have around 10% of their population fully vaccinated."
Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481107/
2 Superiority of Natural Immunity
"This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant."
Source: Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections, August 2021
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1
"Analysis of B and T cell receptor repertoires revealed that while the majority of clonal B and T cells in COVID-19 patients were effector cells, in vaccine recipients clonally expanded cells were primarily circulating memory cells."
Source: New York University, Discrete Immune Response Signature to SARS-CoV-2 mRNA Vaccination Versus Infection, May 2021
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3838993
"People who recover [even] from mild COVID-19 have bone-marrow cells that can churn out antibodies for decades."
Source: Washington Univsity, St. Louis, SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans, May 2021
https://doi.org/10.1038/s41586-021-03647-4
Not 1 of 1,359 previously-infected healthcare workers were re-infected within 10 months into the pandemic in Cleveland's clinic system.
Source: Cleveland Clinic, Necessity of COVID-19 vaccination in previously infected individuals, June 2021
https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v3
"Taken together, these results suggest that broad and effective immunity may persist long-term in recovered COVID-19 patients,"
Source: Emory University, Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00203-2#%20
"Natural infection induced expansion of larger CD8 T cell clones occupied distinct clusters, likely due to the recognition of a broader set of viral epitopes presented by the virus not seen in the mRNA vaccine"
Source: University of Calfornia, Irvine, Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine, July 2021
https://www.biorxiv.org/content/10.1101/2021.07.14.452381v1
In infection-naïve individuals, the second dose boosted the quantity but not quality of the T cell response, while in convalescents the second dose helped neither. Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naïve vaccinees, with phenotypic features suggesting superior long-term persistence and ability to home to the respiratory tract including the nasopharynx."
Source: University of Calfornia, San Francisco, mRNA vaccine-induced SARS-CoV-2-specific T cells recognize B.1.1.7 and B.1.351 variants but differ in longevity and homing properties depending on prior infection status, May 2021
https://www.biorxiv.org/content/10.1101/2021.05.12.443888v1
"In vaccinated subjects, antibody titers decreased by up to 40% each subsequent month while in convalescents they decreased by less than 5% per month."
Source: Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection, August 2021
https://www.medrxiv.org/content/10.1101/2021.08.19.21262111v1
Irish researchers found that, unlike the vaccinated, after 4-6 months there was "no study reporting an increase in the risk of reinfection over time" out of 11 cohort studies with over 600,000 recovered COVID patients.
Source: Quantifying the risk of SARS‐CoV‐2 reinfection over time, April 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209951/pdf/RMV-9999-e2260.pdf
Researchers note that, unlike the many vaccinated breakthrough infections within recent weeks that were symptomatic, "most reinfections were diagnosed incidentally through random or routine testing, or through contact tracing."
Source: Cornell University, SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy, May 2021
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00141-3/fulltext#%20
Israel could only find 1 death case in a recovered, non-vaccinated person out of over 6,000,000 Israelies reviewed in cohort studies.
"As there were only 1 death cases in the Recovered Cohort, protection against death was not estimated.
"Our results question the need to vaccinate previously-infected individuals."
Source: Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel, April 2021
https://www.medrxiv.org/content/10.1101/2021.04.20.21255670v1
Memory B cells in those with prior infection "express increasingly broad and potent antibodies that are resistant to mutations found in variants of concern."
"memory antibodies selected over time by natural infection have greater potency and breadth than antibodies elicited by vaccination."
Source: Rockefeller University,Antibody Evolution after SARS-CoV-2 mRNA Vaccination, July 2021
https://www.biorxiv.org/content/10.1101/2021.07.29.454333v1
h/t: "Horowitz: 15 studies that indicate natural immunity from prior infection is more robust than the COVID vaccines"
No benefit from vaccination for those previously infected: "Individuals who have had SARS-CoV-2 infection are unlikely to benefit from COVID-19 vaccination, and vaccines can be safely prioritized to those who have not been infected before."
June 5, 2021: Necessity of COVID-19 vaccination in previously infected individuals
https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v2
COVID-19 infection produces long-lasting immunity: "Overall, our results indicate that mild infection with SARS-CoV-2 induces robust antigen-specific, long-lived humoral immune memory in humans."
May 24, 2021: SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans
https://www.nature.com/articles/s41586-021-03647-4
Additional study that COVID-19 infection produces life-long immunity: "People who recover from mild COVID-19 have bone-marrow cells that can churn out antibodies for decades, although viral variants could dampen some of the protection they offer."
Had COVID? You’ll probably make antibodies for a lifetime
https://www.nature.com/articles/d41586-021-01442-9
Additional study that COVID-19 infection produces long-term immunity: "these results suggest that broad and effective immunity may persist long-term in recovered COVID-19 patients."
Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells
https://www.medrxiv.org/content/10.1101/2021.04.19.21255739v1
Study Showing Natural Immunity is Superior to Vaccinated Immunity is Replicated by Scientists, with original Israeli study and follow-up study
Protection and waning of natural and hybrid COVID-19 immunity
https://www.medrxiv.org/content/10.1101/2021.12.04.21267114v1
https://www.medrxiv.org/content/10.1101/2021.12.04.21267114v1.full.pdf
Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1.full.pdf
3 Vaccinated Dying of COVID at Higher Rates
""Clinical presentation of myocarditis cases following vaccination has been distinct, occurring most often within one week after dose two, with chest pain as the most common presentation," said Dr. Grace Lee, who chairs the committee’s safety group.""
"most COVID-19 deaths in England are now currently among the vaccinated. Is this a cause for alarm?"
https://medicalxpress.com/news/2021-07-vaccinated-unvaccinated-britons-dying-coronavirus.html
"More vaccinated people are dying of COVID than unvaccinated people, according to a recent report from Public Health England (PHE). The report shows that 163 of the 257 people (63.4%) who died within 28 days of a positive COVID test between February 1 and June 21, had received at least one dose of the vaccine."
"Covid cases in England are THIRTEEN times higher in young people compared to over-60s in more proof of 'vaccine effect' and infections rose in every town except three last week, official figures show"
"Public Health England's weekly surveillance report showed that in the week ending July 4, rates were highest among people in their twenties who have only recently been offered a jab, at 614 per 100,000.:
"Most COVID deaths in England now are in the vaccinated – here’s why that shouldn’t alarm you"
